Avestin headquarters building in Ottawa, Canada

Avestin | Precision High-Pressure Homogenizers & Liposome Extrusion Systems

EmulsiFlex-B15

Minimum Sample: 3 mL

Capacity: 15ml (batch)

EmulsiFlex-C3

Minimum Sample: 10 mL

Capacity: 3L/hr

EmulsiFlex-C5

Minimum Sample: 7 mL

Capacity: 1-5L/hr

EmulsiFlex-D20

Minimum Sample: 50 mL

Capacity: 20 L/hr

EmulsiFlex-C50

Minimum Sample: 25 mL

Capacity: 15-50L/hr

EmulsiFlex-C55

Minimum Sample: 100 mL

Capacity: 55L/hr

EmulsiFlex-C160

Minimum Sample: 250 mL

Capacity: 160L/hr

EmulsiFlex-C500 and C1000 homogenizer systems

EmulsiFlex-C500 & EmulsiFlex-C1000

Minimum Sample: 5 L

Capacity: 500+L/hr

Aseptic homogenizer with 6 sterilization zones

Aseptic Homogenizer with 6 Zones

Four separate zones, including the product zone, are steam-sterilized and separated from two pump zones.

Automatic Pressure Control with Digital Display

This is a simple system which maintains a user-set pressure for the process duration.

LiposoFast

Capacity: 0.1 to 1.0 ml

LiposoFast LF-50

Capacity: 5 to 50 mL

Liposome extruder filter assembly components

Filter & Extruder

Capacity: 15 mL to 160 L/hr

Peak Reset Meter & Transducer

AVESTIN manufactures a flush diaphragm pressure transducer that can measure and display pulsating pressures up to 2000bar/30000psi.

Sanitary Double Tubesheet Heat Exchanger

AVESTIN provides a range of heat exchangers which can be used to control product temperature. All heat exchangers are of high quality and are made of stainless steel.

Static Homogenizing Valve

AVESTIN provides static valves for high-pressure homogenization up to 2000bar/30000psi.

Applications

Nanoparticle dispersion during homogenization

An unprocessed dispersion with a starting size range of 10-100 microns (600X Magnification)

Processed sample of uniform, 1 micron particles (100X Magnification)

Dispersions

A whole range of dispersions can be run through EmulsiFlex high-pressure homogenizers to reduce particle size as well as make the size distribution uniform. EmulsiFlex homogenizers are involved in the processing of dispersions such as drug dispersions, herb extracts, industrial coatings, and pigments. Shown is a sample of a dry crystalline (amorphous) powder run through an EmulsiFlex homogenizer at 25000 psi/173 MPa.

Liposome preparation using high-pressure homogenizer

An Uniform, unilamellar liposomes

Liposomes

AVESTIN's high pressure homogenizers are used all over the world for liposome research and production. Only EmulsiFlex homogenizers offer the combination of high pressure homogenization, high pressure membrane filtration or a combined, homogenization/filtration process.

Liposomes prepared using the EmulsiFlex high-pressure homogenizer, extruder, or both in combination. Combined homogenization yields 113.7 nm in one pass and 89.9 nm in two passes.